Our new Obvious+ tissue clearing procedure is the only real technique that delipidates samples without any adjust in morphology and with minimal impact on structural integrity.
Megatome can be a vibrating microtome meant to section a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform floor profile, together with small tissue destruction and knowledge loss.
Antibodies may well acquire months to diffuse by only some millimeters of tissue, that has a steep labeling gradient from floor to Main.
Megatome is created for precision: the blade vibrates at a better frequency and larger amplitude assortment than other microtomes, and incorporates a special deflection Handle mechanism.
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Megatome is really a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue destruction and data loss.
eFLASH is often a fast tissue labeling system that permits for uniform whole-organ staining in twenty rounds of labeling.
The SmartSPIM light-weight sheet microscope gives unparalleled resolution and acquisition velocity during intact tissue volumes, while its modular megatomi.com layout allows you to up grade and customize specific components.
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SHIELD avoids the variability of hydrogel embedding and the knowledge reduction from PFA preservation, preserving specimens for numerous rounds of processing.
Leverage the Obvious+ tissue clearing process, along with eFLASH and patented stochastic electrotransport technologies, to swiftly crystal clear and label full organs. Key highlights and functions incorporate:
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